Laboratory for Optical and Computational Instrumentation, Department of Biomedical Engineering, University of Wisconsin at Madison, 1675 Observatory Drive, Madison, WI 53706,USA Department of Biomedical Engineering, Oregon Health and Science University, 3303 SW Bond Ave, Portland, OR 97239, USA 3 Department of Dermatology, Oregon Health and Science University, 3303 SW Bond Ave, Portland, OR 97239, USA 4 Electrical Engineering Department, University of Wisconsin-Milwaukee, 3200 N Cramer St., Milwaukee, Wisconsin 53211, USA 5 Morgridge Institute for Research, 330 North Orchard Street, Madison, WI 53715, USA * 2Ībstract: Optimizing light delivery for optogenetics is critical in order to accurately stimulate the neurons of interest while reducing nonspecific effects such as tissue heating or photodamage. OptogenSIM: a 3D Monte Carlo simulation platform for light delivery design in optogenetics Yuming Liu,1 Steven L.
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